Official position
Full Professor and Director of the Institue of Medical Infrmatics, Statistics and Epidemiology Leipzig
Institution
Institute of Medical Informatics, Statistics and Epidemiology Leipzig
Business address
Härtelstr. 16-18
04107 Leipzig
Academic education and degrees
1974 - 1980 | Study of Medicine at Universtiy of Köln |
1974 - 1982 | Study of Physics at University of Köln |
1980 | Approbation to practise medicine |
1982 | Diploma in Physics |
1983 | Dissertation
(Dr. med.), University Köln |
1990 | Habilitation
and Venia Legendi in Medical Documentation, Statistics and Biomathematics,
University Köln |
1993 | Sabbatical
Leave, Dept. Statistics, University Reading, England |
Professional career
1980 - 1984 | Research
assistant Biometry, University Köln |
1984 - 1994 | Research
group leader Biometry, University Köln |
Since 1994 | Full
Professor and Director of the Institute of Medical Informatics, Statistics and
Epidemiology Leipzig (IMISE) |
Since 1999 | Scientific
Director of the Center of Clinical Trials Leipzig (ZKS) |
Since 2001 | Scientific
Director of the Interdisciplinary Center for Bioinformatics (IZBI) |
Since 2009 | Scientific
Director of the LIFE Research Center for Civilization Diseases |
Honors, awards and positions
| Member of the Program Commission of the System
Medicine Consortia (e:MED) |
| Member of the National Steering Committee of the
Medical Informatics Initiative (MI-I) |
| Board of Directors of the German National Cohort
(GNC) |
Since 2018 | PI
of The SMITH Consortium of the Medical Informatics Initiative |
9 most important peer-reviewed papers (10 out of 394, Scopus h-index: 87)
Winter A, Stäubert S, Ammon D, …, Löffler M. Smart Medical Information Technology for Healthcare (SMITH). Methods Inf Med. 2018;57(S 01):e92-e105.
Loeffler M, Engel C, Ahnert P, Alfermann D, Arelin K, et al. The LIFE-Adult-Study: objectives and design of a population-based cohort study with 10,000 deeply phenotyped adults in Germany. BMC Public Health. 2015;15:691.
Spada J, Scholz M, Kirsten H, …, Loeffler M, et al. Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study. J Sleep Res. 2016;25(6):690-701.
Kharabian Masouleh S, Beyer F, Lampe L, Loeffler M, et al. Gray matter structural networks are associated with cardiovascular risk factors in healthy older adults. J Cereb Blood Flow Metab. 2018;38(2):360-372.
Vojinovic D, Adams HH, Jian X, …, Loeffler M, et al. Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume. Nat Commun. 2018;9(1):3945.
Satizabal CL, Adams HHH, Hibar DP, …, Loeffler M, et al. Genetic architecture of subcortical brain structures in 38,851 individuals. Nat Genet. 2019;51(11):1624-1636.
Yahiaoui-Doktor M, Luck T, Riedel-Heller SG, Loeffler M, Wirkner K, Engel C. Olfactory function is associated with cognitive performance: results from the population-based LIFE-Adult-Study. Alzheimers Res Ther. 2019;11(1):43.
Bloos F, Trips E, Nierhaus A, …, Loeffler M, Reinhart K; for SepNet Critical Care Trials Group. Effect of Sodium Selenite Administration and Procalcitonin-Guided Therapy on Mortality in Patients With Severe Sepsis or Septic Shock: A Randomized Clinical Trial. JAMA Intern Med. 2016;176(9):1266-76.
Chapuy B, Stewart C, Dunford AJ, …, Loeffler M, et al. Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes. Nat Med. 2018;24(5):679-690.
