Arbeitsgruppe PD Dr. Markus Schwab - Molekulare Regulation neuraler Netzwerke

ORCID-ID: 0000-0003-2477-2892​

Hernández S., Salvany S., Casanovas A., Piedrafita L., Soto-Bernardini M.C., Tarabal O., Blasco A., Gras S., Gatius A., Schwab M.H.*, Calderó J., Esquerda J.E. (2023). Persistent NRG1 type III overexpression in spinal motor neurons has no therapeutic effect on ALS-related pathology in SODG93A mice. Neurotherapeutics. 20, 1820-1834. *senior co-author
 
Götze T., Soto Bernardini M.C., Zhang M., Mießner H., Brzózka M.M., Velanac V., Dullin C., Ramos-Gomes F., Peng M., Husseini H., Schifferdecke E., Alves F., Rossner M.J., Nave K.A., Zhang W., Schwab M.H. (2021). Hyperactivity is a core endophenotype of elevated juxtacrine Neuregulin-1 signaling in embryonic glutamatergic networks.
Schizophr. Bull. 47, 1409-1420.
  
Fledrich R., Akkermann D., Abdelaal T.A., Schuetza V., Hermes D., Schäffner E., Soto-Bernadini M.C., Götze T., Klink A., Kusch K., Krüger M., Moebius W., Brück W., Mueller W.C., Sereda M.W., Schwab M.H.*, Nave K.A., Stassart R.M. (2019). A Neuregulin-1 type I signaling axis mediates Schwann cell interactions upstream of disease hallmarks in the most common inherited demyelinating neuropathy. Nature Commun. 10,1467.
*joint corresponding author
 
Salvany S., Casanovas A., Tarabal O., Piedrafita L., Hernández S., Santafé M., Soto-Bernardini M.C., Calderó J., Schwab M.H.*, Esquerda J.E. (2019). Localization and dynamic changes of neuregulin-1 at C-type synaptic boutons in association with motor neuron injury and repair. FASEB J. 33, 7833-7851. *joint corresponding author
 
Wehr M.C., Hinrichs W., Brzózka M.M., Unterbarnscheidt T., Herholt A., Wintgens J.P., Soto-Bernardini M.C., Kravchenko M., Nave K.A., Wichert S.P., Falkai P., Zhang W., Schwab M.H., Rossner M.J. (2017). Spironolactone is an antagonist of NRG1-ERBB4 signaling and schizophrenia-relevant endophenotypes in mice. EMBO Mol Med. 9, 1448-1462.
 
Lee Y., Li Y., Mikesh M., Smith I., Nave K.A., Schwab M.H., Thompson W.J. (2016). Neuregulin1 displayed on motor axons regulates terminal Schwann cell-mediated synapse elimination at developing neuromuscular junctions. Proc Natl Acad Sci. 113, E479-87.
 
Agarwal A., Zhang M., Trembak-Duff I., Unterbarnscheidt T., Radyushkin K., Dibaj P., Martins de Souza D., Boretius S., Brzózka M.M., Steffens H., Berning S., Teng Z., Gummert M., Tantra M., Guest P.C., Willig K.I., Frahm J., Hell S.W., Bahn S., Rossner M.J., Nave K.A., Ehrenreich H., Zhang W., Schwab M.H. (2014). Dysregulated expression of neuregulin-1 by cortical pyramidal neurons disrupts synaptic plasticity. Cell Rep. 8,1130-1145.