Neurocognitive mechanisms are crucial to the understanding of mental disorders. Cognitive processes such as executive functions, decision making, instrumental and Pavlovian learning, motivation or affective and social cognitive processes contribute to the dysfunction in action control observable for example in patients with addictive disorders and eating disorders. Underlying cognitive processes can be inferred by computational modelling of overt behaviour. Mapping the dynamic cognitive computations to brain activity assessed with functional MRI accelerates the identification of the involved brain systems. By combining behavioural testing and imaging techniques with genetic, pharmacologic and endocrinologic methods, the molecular, neurochemical, neuropharmacological and neuroendocrinological mechanisms are explored. Research at the Max Planck Institute for Human Cognitive and Brain Sciences (MPI CBS) in Leipzig revolves around human cognitive abilities and cerebral processes, with a focus on the neural basis of brain functions such as language, memory, navigation, music, and communication. The MPI uses cutting edge equipment (MRI (7T, 3T, Connectome), EEG, MEG, fNIRS, TMS, TDCS, focused ultrasound) to examine mind-body-brain interactions. Projects involve the impact of psychosocial stress on brain structure and function; chronic impact of stress on development of hypertension, obesity; the mutual developmental/causal relationship between depression and stroke/dementia. Other projects focus on emotion regulation and its neural correlates and interventions, and on cardiac determinants of mental health and cognition.
Mental Health Dresden-Leipzig is involved in the following selected projects:
CRC 940
CRC TRR 265
AERIAL
FOR 2698
ASD-Net