The Paul Flechsig Institute has a wide range of methods at its disposal that are used in neuroscientific research. These methods are used to investigate the neuronal basis of pathological processes, both in the brain and in peripheral neuronal tissue, in order to gain a comprehensive insight into its functioning.
An important part of the Institute's range of methods is the imaging and histological processing of neural tissue. Various state-of-the-art high-resolution microscopes enable the imaging of the smallest tissue structures through to the three-dimensional reconstruction of entire cells or cell clusters. This makes it possible to visualize changes in the brain and nerve tissue and is therefore a valuable tool for investigating fundamental neuronal processes.
In addition, the Paul Flechsig Institute uses a variety of other methods ranging from basic molecular biology methods and in vitro experiments to advanced protein biochemical analyses such as enzyme kinetics and flow cytometry. The focus is primarily on gene expression analyses at the single-cell level, which can provide information about the interaction and activity of various cells.
In addition, the Paul Flechsig Institute has an animal behavioral biology laboratory in which analytical methods of learning and memory are used.